An unusual organoid tumor. Alveolar soft part sarcoma or paraganglioma?

Debra S. Heller, Cheryl P. Frydman, Ronald E. Gordon, Jashree Jagirdar, Ira S. Schwartz

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

The histogenesis of alveolar soft part sarcoma (ASPS) is a subject of continued debate. Although many recent reports suggest a muscle origin, others advocate a neuroendocrine derivation. A tumor in the chest wall of a 16‐year‐old woman was diagnosed and treated as ASPS. The light microscopic, electron microscopic, and immunohistochemical findings showed features of both ASPS and paraganglioma. In addition, this lesion was positive for antibody to glucagon, a characteristic of neither ASPS nor paraganglioma, although seen in a few gangliocytic paragangliomas. This case demonstrates the need for continued inquiry into the histogenesis of ASPS.

Original languageEnglish (US)
Pages (from-to)1894-1899
Number of pages6
JournalCancer
Volume67
Issue number7
DOIs
StatePublished - Apr 1 1991

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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