An Overview of Negative Pressure Wound Therapy for the Lower Extremity

Claire M. Capobianco, Thomas Zgonis

Research output: Contribution to journalReview articlepeer-review

24 Scopus citations


Since its introduction into the market, negative pressure wound therapy (NPWT), also known as topical negative pressure, has become an important adjuvant therapy for the treatment of many types of wounds. Surgeons and physicians of all subspecialties have adopted NPWT into their practices. NPWT has become a mainstay in the management of lower extremity soft tissue pathology, especially in patients with traumatic, diabetic, postsurgical, and peripheral vascular disease-associated wounds. This article reviews the background, currently understood mechanisms of action, applications, contraindications, reported complications, advantages, criticisms, and techniques in the lower extremity.

Original languageEnglish (US)
Pages (from-to)619-631
Number of pages13
JournalClinics in podiatric medicine and surgery
Issue number4
StatePublished - Oct 2009


  • Diabetic foot
  • Diabetic neuropathy
  • Diabetic ulcers
  • Lower extremity
  • Negative pressure wound therapy

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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