An evaluation of kits for measuring thyrotropin in newborns

E. A. Pierson, B. L. Therrell, S. F. Franz, A. J. Rudenstein, P. E. Dziuk

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Several commercial radioimmunoassay kits are now marketed specially for determination of thyrotropin (TSH) from whole-blood specimens collected on filter paper in neonatal screening programs. We have compared five kits in use in such screening programs in the United States. The reagent kits from Becton Dickinson, Neometrics, and Nuclear Medical Systems gave similar satisfactory results. That from Pharmacia was somewhat more difficult to use and gave greater coefficients of variation. Diagnostic Products' kit appeared to perform satisfactorily, but the analytical values obtained were significantly low, which may suggest erroneous calibrator values within the kit.

Original languageEnglish (US)
Pages (from-to)1854-1856
Number of pages3
JournalClinical Chemistry
Volume30
Issue number11
StatePublished - Dec 1 1984
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

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  • Cite this

    Pierson, E. A., Therrell, B. L., Franz, S. F., Rudenstein, A. J., & Dziuk, P. E. (1984). An evaluation of kits for measuring thyrotropin in newborns. Clinical Chemistry, 30(11), 1854-1856.