Amphotericin B-impregnated bone cement to treat refractory coccidioidal osteomyelitis

Elizabeth S. Zhu, George R. Thompson, Christopher Kreulen, Eric Giza

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Use of amphotericin B-impregnated bone cement in combination with systemic antifungals for the treatment of coccidioidal osteomyelitis offers the potential for sustained local concentrations of drug at the site of the infection. Amphotericin B levels in bone of up to 5.1 μg/g have been demonstrated 4 months after placement of bone cement.

Original languageEnglish (US)
Pages (from-to)6341-6343
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume57
Issue number12
DOIs
StatePublished - Dec 2013
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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