Amniotic Membrane Transplantation with Fibrin Glue for Conjunctivochalasis

Ahmad Kheirkhah; Victoria Casas; Gabriela Blanco; Wei Li; Yasutaka Hayashida; Ying Ting Chen; Scheffer C.G. Tseng

doi:10.1016/j.ajo.2007.03.044

Amniotic Membrane Transplantation with Fibrin Glue for Conjunctivochalasis

Ahmad Kheirkhah, Victoria Casas, Gabriela Blanco, Wei Li, Yasutaka Hayashida, Ying Ting Chen, Scheffer C.G. Tseng

Research output: Contribution to journal › Article › peer-review

63 Scopus citations

Abstract

Purpose: To evaluate the feasibility of performing sutureless amniotic membrane transplantation (AMT) using fibrin glue for conjunctivochalasis. Design: Noncomparative interventional case series. Methods: In 25 eyes of 16 patients with refractory conjunctivochalasis (CCh), AMT using fibrin glue was performed to cover the bare sclera. Results: The mean age was 55.2 ± 18.5 years with nine patients (56.2%) younger than 60 years. The Tenon capsule was dissolved in all eyes. Fibrin glue was effective in securing the amniotic membrane to the sclera. For a mean follow-up of 10.6 ± 4.3 months, all eyes achieved a smooth conjunctival surface with complete or significant improvement of symptoms in 44% and 56%, respectively. Complications included focal conjunctival inflammation in four eyes and pyogenic granuloma in one eye. Conclusion: AMT using fibrin glue can be performed for refractory CCh resulting in alleviating its symptoms and signs.

Original language	English (US)
Pages (from-to)	311-313
Number of pages	3
Journal	American journal of ophthalmology
Volume	144
Issue number	2
DOIs	https://doi.org/10.1016/j.ajo.2007.03.044
State	Published - Aug 2007
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

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@article{aaaac6bd0ff54cdda9f11974087bd5d6,

title = "Amniotic Membrane Transplantation with Fibrin Glue for Conjunctivochalasis",

abstract = "Purpose: To evaluate the feasibility of performing sutureless amniotic membrane transplantation (AMT) using fibrin glue for conjunctivochalasis. Design: Noncomparative interventional case series. Methods: In 25 eyes of 16 patients with refractory conjunctivochalasis (CCh), AMT using fibrin glue was performed to cover the bare sclera. Results: The mean age was 55.2 ± 18.5 years with nine patients (56.2%) younger than 60 years. The Tenon capsule was dissolved in all eyes. Fibrin glue was effective in securing the amniotic membrane to the sclera. For a mean follow-up of 10.6 ± 4.3 months, all eyes achieved a smooth conjunctival surface with complete or significant improvement of symptoms in 44% and 56%, respectively. Complications included focal conjunctival inflammation in four eyes and pyogenic granuloma in one eye. Conclusion: AMT using fibrin glue can be performed for refractory CCh resulting in alleviating its symptoms and signs.",

author = "Ahmad Kheirkhah and Victoria Casas and Gabriela Blanco and Wei Li and Yasutaka Hayashida and Chen, {Ying Ting} and Tseng, {Scheffer C.G.}",

note = "Funding Information: This study was supported by Joe Swiger and Eye Foundation of America Fellowship (Dr Kheirkhah) from Ocular Surface Research and Education Foundation, Miami, Florida. Dr Tseng and his family are more than 5% shareholders of TissueTech, Inc, which owns US patents 6,152,142 and 6,326,019 on the method of preparation and clinical uses of human amniotic membrane distributed by Bio-Tissue, Inc. Involved in design and conduct of study (A.K., S.C.G.T.); data collection (A.K., V.C., W.L., G.B., Y.H., Y.T.C.); provision of materials (V.K.R., S.C.G.T.); interpretation and writing the article (A.K., S.C.G.T.); and administrative support (V.K.R., S.C.G.T.). This study was approved by Institutional Review Board of Baptist Hospital, Miami, Florida.",

year = "2007",

month = aug,

doi = "10.1016/j.ajo.2007.03.044",

language = "English (US)",

volume = "144",

pages = "311--313",

journal = "American journal of ophthalmology",

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TY - JOUR

T1 - Amniotic Membrane Transplantation with Fibrin Glue for Conjunctivochalasis

AU - Kheirkhah, Ahmad

AU - Casas, Victoria

AU - Blanco, Gabriela

AU - Li, Wei

AU - Hayashida, Yasutaka

AU - Chen, Ying Ting

AU - Tseng, Scheffer C.G.

N1 - Funding Information: This study was supported by Joe Swiger and Eye Foundation of America Fellowship (Dr Kheirkhah) from Ocular Surface Research and Education Foundation, Miami, Florida. Dr Tseng and his family are more than 5% shareholders of TissueTech, Inc, which owns US patents 6,152,142 and 6,326,019 on the method of preparation and clinical uses of human amniotic membrane distributed by Bio-Tissue, Inc. Involved in design and conduct of study (A.K., S.C.G.T.); data collection (A.K., V.C., W.L., G.B., Y.H., Y.T.C.); provision of materials (V.K.R., S.C.G.T.); interpretation and writing the article (A.K., S.C.G.T.); and administrative support (V.K.R., S.C.G.T.). This study was approved by Institutional Review Board of Baptist Hospital, Miami, Florida.

PY - 2007/8

Y1 - 2007/8

N2 - Purpose: To evaluate the feasibility of performing sutureless amniotic membrane transplantation (AMT) using fibrin glue for conjunctivochalasis. Design: Noncomparative interventional case series. Methods: In 25 eyes of 16 patients with refractory conjunctivochalasis (CCh), AMT using fibrin glue was performed to cover the bare sclera. Results: The mean age was 55.2 ± 18.5 years with nine patients (56.2%) younger than 60 years. The Tenon capsule was dissolved in all eyes. Fibrin glue was effective in securing the amniotic membrane to the sclera. For a mean follow-up of 10.6 ± 4.3 months, all eyes achieved a smooth conjunctival surface with complete or significant improvement of symptoms in 44% and 56%, respectively. Complications included focal conjunctival inflammation in four eyes and pyogenic granuloma in one eye. Conclusion: AMT using fibrin glue can be performed for refractory CCh resulting in alleviating its symptoms and signs.

AB - Purpose: To evaluate the feasibility of performing sutureless amniotic membrane transplantation (AMT) using fibrin glue for conjunctivochalasis. Design: Noncomparative interventional case series. Methods: In 25 eyes of 16 patients with refractory conjunctivochalasis (CCh), AMT using fibrin glue was performed to cover the bare sclera. Results: The mean age was 55.2 ± 18.5 years with nine patients (56.2%) younger than 60 years. The Tenon capsule was dissolved in all eyes. Fibrin glue was effective in securing the amniotic membrane to the sclera. For a mean follow-up of 10.6 ± 4.3 months, all eyes achieved a smooth conjunctival surface with complete or significant improvement of symptoms in 44% and 56%, respectively. Complications included focal conjunctival inflammation in four eyes and pyogenic granuloma in one eye. Conclusion: AMT using fibrin glue can be performed for refractory CCh resulting in alleviating its symptoms and signs.

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Amniotic Membrane Transplantation with Fibrin Glue for Conjunctivochalasis

Abstract

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