Amine Precursors and Depression

Joe Mendels; James L. Stinnett; David Burns; Alan Frazer

doi:10.1001/archpsyc.1975.01760190024002

Amine Precursors and Depression

Joe Mendels
, James L. Stinnett
, David Burns
, Alan Frazer

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

Abstract

The amino acid precursors, levodopa and L-tryptophan, were given to a group of hospitalized depressed patients in a double-blind placebo controlled study. Relatively large doses were not associated with sufficient clinical improvement to allow the patients to leave the hospital. Previous studies using the precursor-load strategy have produced conflicting findings on the use of these compounds for depressed patients.

Original language	English (US)
Pages (from-to)	22-30
Number of pages	9
Journal	Archives of General Psychiatry
Volume	32
Issue number	1
DOIs	https://doi.org/10.1001/archpsyc.1975.01760190024002
State	Published - Jan 1975
Externally published	Yes

ASJC Scopus subject areas

Psychiatry and Mental health
Arts and Humanities (miscellaneous)

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10.1001/archpsyc.1975.01760190024002

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@article{9b039f6d989d4214a1a4864c67041138,

title = "Amine Precursors and Depression",

abstract = "The amino acid precursors, levodopa and L-tryptophan, were given to a group of hospitalized depressed patients in a double-blind placebo controlled study. Relatively large doses were not associated with sufficient clinical improvement to allow the patients to leave the hospital. Previous studies using the precursor-load strategy have produced conflicting findings on the use of these compounds for depressed patients.",

author = "Joe Mendels and Stinnett, \{James L.\} and David Burns and Alan Frazer",

year = "1975",

month = jan,

doi = "10.1001/archpsyc.1975.01760190024002",

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journal = "Archives of General Psychiatry",

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AU - Mendels, Joe

AU - Stinnett, James L.

AU - Burns, David

AU - Frazer, Alan

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N2 - The amino acid precursors, levodopa and L-tryptophan, were given to a group of hospitalized depressed patients in a double-blind placebo controlled study. Relatively large doses were not associated with sufficient clinical improvement to allow the patients to leave the hospital. Previous studies using the precursor-load strategy have produced conflicting findings on the use of these compounds for depressed patients.

AB - The amino acid precursors, levodopa and L-tryptophan, were given to a group of hospitalized depressed patients in a double-blind placebo controlled study. Relatively large doses were not associated with sufficient clinical improvement to allow the patients to leave the hospital. Previous studies using the precursor-load strategy have produced conflicting findings on the use of these compounds for depressed patients.

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UR - https://www.scopus.com/pages/publications/0016427660#tab=citedBy

U2 - 10.1001/archpsyc.1975.01760190024002

DO - 10.1001/archpsyc.1975.01760190024002

M3 - Article

C2 - 1089400

AN - SCOPUS:0016427660

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VL - 32

SP - 22

EP - 30

JO - Archives of General Psychiatry

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Amine Precursors and Depression

Abstract

ASJC Scopus subject areas

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