Amended safety assessment of hypericum perforatum-derived ingredients as used in cosmetics

Lillian C. Becker, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, F. Alan Andersen, Lillian J. Gill

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

The Cosmetic Ingredient Review Expert Panel (Panel) has issued an amended safety assessment of 7 Hypericum perforatum-derived ingredients as used in cosmetics. A common name for this plant is St John wort. These ingredients function in cosmetics as skin-conditioning agents - miscellaneous and antimicrobial agents. The Panel reviewed relevant animal and human data related to the H perforatum-derived ingredients. Because formulators may use more than 1 botanical ingredient in a formulation, caution was urged to avoid levels of toxicological concern for constituent chemicals and impurities. The Panel concluded that H perforatum-derived ingredients were safe as cosmetic ingredients in the practices of use and concentration as described in this safety assessment.

Original languageEnglish (US)
Pages (from-to)5S-23S
JournalInternational journal of toxicology
Volume33
Issue number6
DOIs
StatePublished - Sep 13 2014

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Keywords

  • Hypericum perforatum

ASJC Scopus subject areas

  • Toxicology

Cite this

Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., Andersen, F. A., & Gill, L. J. (2014). Amended safety assessment of hypericum perforatum-derived ingredients as used in cosmetics. International journal of toxicology, 33(6), 5S-23S. https://doi.org/10.1177/1091581814533354