Alveolar Cell Carcinoma-like Antigen and Antibodies in Patients with Alveolar Cell Carcinoma and Other Cancers

John A. Mohr, Robert E. Nordquist, Everett R. Rhoades, Robert E. Coalson, Jacqueline J. Coalson

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Antiserum was produced in sheep against a particle pellet recovered from human alveolar cell carcinoma (ACC). The antiserum was used for the detection of similar antigens in patients with ACC using the immunodiffusion method. Tumor cell lines were used in the indirect fluorescent technique for the detection of antibodies in the serum of patients with tumors and control serum. The results indicate that similar antigens are present in the serum of some patients with ACC, primary adenocarcinoma of the lung, and Hodgkin's disease. Antibodies develop in some patients with ACC and primary adenocarcinoma of the lung and in sheep inoculated with the agent.

Original languageEnglish (US)
Pages (from-to)1904-1907
Number of pages4
JournalCancer Research
Volume34
Issue number8
StatePublished - Aug 1 1974

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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