Alternative transcripts of the rat and human dopamine D3 receptor

Lenore A. Snyder; James L. Roberts; Stuart C. Sealfon

doi:10.1016/S0006-291X(05)81169-6

Alternative transcripts of the rat and human dopamine D3 receptor

Lenore A. Snyder, James L. Roberts, Stuart C. Sealfon

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A cDNA for the rat dopamine D3 receptor containing a 113 bp deletion has been isolated. The segment deleted, encompassing the first extracellular loop and third transmembrane domain, alters the reading frame, introducing 19 amino acids not found in the full length receptor followed by a premature stop codon. This novel mRNA encodes a 109 amino acid protein containing two putative tranmembrane domains. A similar variant cDNA for the human D₃ receptor has also been identified.

Original language	English (US)
Pages (from-to)	1031-1035
Number of pages	5
Journal	Biochemical and Biophysical Research Communications
Volume	180
Issue number	2
DOIs	https://doi.org/10.1016/S0006-291X(05)81169-6
State	Published - Oct 31 1991
Externally published	Yes

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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10.1016/S0006-291X(05)81169-6

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AU - Roberts, James L.

AU - Sealfon, Stuart C.

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Alternative transcripts of the rat and human dopamine D3 receptor

Abstract

ASJC Scopus subject areas

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