Abstract
Acute insulin stress increased plasma catecholamine levels in both the Syrian hamster and albino rat within 3 h after an intraperitoneal injection of either 5 or 10 units of insulin. In the rat, this stress caused a concurrent increase in pineal serotonin N-acetyltransferase (NAT) activity and melatonin content with no observable change in hydroxyindole-O-methyltransferase (HIOMT) activity. In the hamster, on the other hand, acute insulin stress did not alter pineal NAT activity, but depressed both HIOMT activity and melatonin content up to 3 h after the stress. These results present further evidence that catecholamines do not control hamster pineal melatonin synthesis by the same mechanism as observed in the rat.
Original language | English (US) |
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Pages (from-to) | 25-32 |
Number of pages | 8 |
Journal | Brain Research |
Volume | 338 |
Issue number | 1 |
DOIs | |
State | Published - Jul 8 1985 |
Keywords
- Syrian hamster
- albino rat
- catecholamines
- melatonin
- pineal
- stress
ASJC Scopus subject areas
- Neuroscience(all)
- Molecular Biology
- Clinical Neurology
- Developmental Biology