All-optical optoacoustic microscopy based on probe beam deflection technique

Saher M. Maswadi, Bennett L. Ibey, Caleb C. Roth, Dmitri A. Tsyboulski, Hope T. Beier, Randolph D. Glickman, Alexander A. Oraevsky

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Optoacoustic (OA) microscopy using an all-optical system based on the probe beam deflection technique (PBDT) for detection of laser-induced acoustic signals was investigated as an alternative to conventional piezoelectric transducers. PBDT provides a number of advantages for OA microscopy including (i) efficient coupling of laser excitation energy to the samples being imaged through the probing laser beam, (ii) undistorted coupling of acoustic waves to the detector without the need for separation of the optical and acoustic paths, (iii) high sensitivity and (iv) ultrawide bandwidth. Because of the unimpeded optical path in PBDT, diffraction-limited lateral resolution can be readily achieved. The sensitivity of the current PBDT sensor of 22 μV/Pa and its noise equivalent pressure (NEP) of 11.4 Pa are comparable with these parameters of the optical micro-ring resonator and commercial piezoelectric ultrasonic transducers. Benefits of the present prototype OA microscope were demonstrated by successfully resolving micron-size details in histological sections of cardiac muscle.

Original languageEnglish (US)
Pages (from-to)91-101
Number of pages11
JournalPhotoacoustics
Volume4
Issue number3
DOIs
StatePublished - Sep 1 2016

Keywords

  • All optical optoacoustic system
  • Backward mode optoacoustic microscopy
  • Non-contact acoustic sensor
  • Optical resolution photoacoustic imaging
  • Optoacoustic tomography
  • Probe beam deflection technique

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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