Alkylating agent-induced NRF2 blocks endoplasmic reticulum stress-mediated apoptosis via control of glutathione pools and protein thiol homeostasis

Biochemistry, Genetics and Molecular Biology

• Endoplasmic Reticulum Stress 100%
• Thiol 66%
• Homeostasis 50%
• Glutathione 50%
• KEAP1 50%
• Protein 50%
• Apoptosis 33%
• GCLM 33%
• GCLC 33%
• Survival 33%
• Protein Characterization 33%
• Cancer Cell 16%
• Mutation 16%
• Nested Gene 16%
• Upregulation 16%
• Acetylcysteine 16%
• Cell Death 16%
• Lysozyme 16%
• Gene Expression Profiling 16%
• Myc 16%
• Synthesis 16%
• Buthionine Sulfoximine 16%
• NFE2L2 16%
• Drug Detoxification 16%
• Comprehension 16%
• Mutant 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Alkylating Agent 83%
• Protein 50%
• Toxicity 33%
• Glutathione 33%
• Drug 33%
• Survival 33%
• Apoptosis 33%
• Enzyme 16%
• Anticarcinogen 16%
• Antioxidant 16%
• Acetylcysteine 16%
• Malignant Neoplasm 16%
• Cell Death 16%
• Buthionine Sulfoximine 16%
• Head and Neck Carcinoma 16%
• Drug Detoxification 16%
• Glutathione Ethyl Ester 16%