Aggressive ossifying fibroma of the maxilla: Review of the literature and report of case

A case of a large aggressive ossifying fibroma of the maxilla has been presented. Review of the literature shows the difficulty in establishing a definitive diagnosis through any single diagnostic modality. Much of this is due to the confusion surrounding classification of the tumor. Adjunctive radiographic and nuclear medicine diagnostic aids were utilized, as were clinical, laboratory, and histopathologic studies, in resolving the diagnostic questions posed by this large and aggressive tumor. Surgical intervention through conservative enucleation produced few operative or postoperative difficulties and minimal residual deformity. Differentiation of ossifying fibroma from other benign and malignant neoplasms as well as fibrous dysplasia is important in the correct management of this lesion.