Age‐related changes in the intact and sympathetically denervated gerbil pineal gland

Russel J. Reiter, Marcia G. Welsh, Mary K. Vaughan

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


The pineal gland of four‐month‐old gerbils contains numerous calcareous deposits (corpora arenacea or concretions). Also, the tissue appears vacuolated due to the presence of a number of large rounded spaces. The deposits are usually associated with or lying within these “vacuoles”. By eight months of age, the number of both the corpora arenacea and the “vacuoles” are increased over those present in the pineals of four‐month‐old gerbils. Bilateral superior cervical ganglionectomy at one month of age prevents the formation of both the concretions and “vacuoles”. The cells in the sympathetically denervated pineal glands are smaller than those in pineal glands of animals that possess intact superior cervical ganglia.

Original languageEnglish (US)
Pages (from-to)427-432
Number of pages6
JournalAmerican Journal of Anatomy
Issue number4
StatePublished - Aug 1976

ASJC Scopus subject areas

  • Anatomy


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