Abstract
In this review the structural and chemical nature of the input fibers of hippocampus and their relationships to estrogen-ceptive neurons were discussed. The interactions of estrogen with catecholaminergic and peptidergic synaptic transmissions concerning limbic function became apparent; the cyclic changes in circulating estrogen in the reproductive animals create the cyclic changes in the activity of the hippocampal function; therefore, in the aged animals, the cessation of cyclic changes in circulating estrogen suppresses the activity of hippocampal function, and thus may lead to the initiation of Alzheimer's disease in man.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 85-108 |
| Number of pages | 24 |
| Journal | Biomedical Research |
| Volume | 2 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1981 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)