Age-related decrease in the naive (OX22+) T cells in F344 rats

Mohammad A. Pahlavani, Arlan Richardson

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

The frequency of the cells bearing the naive marker (OX22+) in T cells, helper, and cytotoxic/suppressor T cell subsets isolated from the spleens of young and old F344 rats were measured by flow cytometry. The percentage of naive cells in T cells decreased significantly with age and this decline occurred primarily in the helper subset.

Original languageEnglish (US)
Pages (from-to)171-176
Number of pages6
JournalMechanisms of Ageing and Development
Volume74
Issue number3
DOIs
StatePublished - Jun 1994

Keywords

  • Aging
  • Naive (OX22+) T Cells
  • Rat

ASJC Scopus subject areas

  • Aging
  • Developmental Biology

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