Age-related decrease in the naive (OX22+) T cells in F344 rats

Mohammad A. Pahlavani; Arlan Richardson

doi:10.1016/0047-6374(94)90088-4

Age-related decrease in the naive (OX22+) T cells in F344 rats

Mohammad A. Pahlavani, Arlan Richardson

Barshop Institute

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

The frequency of the cells bearing the naive marker (OX22+) in T cells, helper, and cytotoxic/suppressor T cell subsets isolated from the spleens of young and old F344 rats were measured by flow cytometry. The percentage of naive cells in T cells decreased significantly with age and this decline occurred primarily in the helper subset.

Original language	English (US)
Pages (from-to)	171-176
Number of pages	6
Journal	Mechanisms of Ageing and Development
Volume	74
Issue number	3
DOIs	https://doi.org/10.1016/0047-6374(94)90088-4
State	Published - Jun 1994

Keywords

Aging
Naive (OX22+) T Cells
Rat

ASJC Scopus subject areas

Aging
Developmental Biology

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10.1016/0047-6374(94)90088-4

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title = "Age-related decrease in the naive (OX22+) T cells in F344 rats",

abstract = "The frequency of the cells bearing the naive marker (OX22+) in T cells, helper, and cytotoxic/suppressor T cell subsets isolated from the spleens of young and old F344 rats were measured by flow cytometry. The percentage of naive cells in T cells decreased significantly with age and this decline occurred primarily in the helper subset.",

keywords = "Aging, Naive (OX22+) T Cells, Rat",

author = "Pahlavani, {Mohammad A.} and Arlan Richardson",

note = "Funding Information: This research was supported by grants AG-00165 and AG-01548 awarded by the National Institute on Aging. We thank Ms Sheryl Dorsey for her technical assistance with the flow cytometry.",

year = "1994",

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AU - Pahlavani, Mohammad A.

AU - Richardson, Arlan

N1 - Funding Information: This research was supported by grants AG-00165 and AG-01548 awarded by the National Institute on Aging. We thank Ms Sheryl Dorsey for her technical assistance with the flow cytometry.

PY - 1994/6

Y1 - 1994/6

N2 - The frequency of the cells bearing the naive marker (OX22+) in T cells, helper, and cytotoxic/suppressor T cell subsets isolated from the spleens of young and old F344 rats were measured by flow cytometry. The percentage of naive cells in T cells decreased significantly with age and this decline occurred primarily in the helper subset.

AB - The frequency of the cells bearing the naive marker (OX22+) in T cells, helper, and cytotoxic/suppressor T cell subsets isolated from the spleens of young and old F344 rats were measured by flow cytometry. The percentage of naive cells in T cells decreased significantly with age and this decline occurred primarily in the helper subset.

KW - Aging

KW - Naive (OX22+) T Cells

KW - Rat

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ER -

Age-related decrease in the naive (OX22+) T cells in F344 rats

Abstract

Keywords

ASJC Scopus subject areas

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