Age-related changes in unscheduled DNA synthesis by rat hepatocytes

Marguerite M. Plesko, Arlan Richardson

Research output: Contribution to journal › Article

24 Citations (Scopus)

Abstract

Ultraviolet-induced unscheduled DNA synthesis was studied as a function of age in hepatocytes isolated from 6- to 32-months-old rats. Unscheduled DNA synthesis was measured by both DNA specific activity and autoradiography. Using both procedures, a significant decline in unscheduled DNA synthesis was observed after 14 months of age.

Original languageEnglish (US)
Pages (from-to)730-735
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume118
Issue number3
DOIs
StatePublished - Feb 14 1984
Externally publishedYes

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Rats
Hepatocytes
DNA
Autoradiography

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Age-related changes in unscheduled DNA synthesis by rat hepatocytes. / Plesko, Marguerite M.; Richardson, Arlan.

In: Biochemical and Biophysical Research Communications, Vol. 118, No. 3, 14.02.1984, p. 730-735.

Research output: Contribution to journal › Article

Plesko, MM & Richardson, A 1984, 'Age-related changes in unscheduled DNA synthesis by rat hepatocytes', Biochemical and Biophysical Research Communications, vol. 118, no. 3, pp. 730-735. https://doi.org/10.1016/0006-291X(84)91455-4
Plesko MM, Richardson A. Age-related changes in unscheduled DNA synthesis by rat hepatocytes. Biochemical and Biophysical Research Communications. 1984 Feb 14;118(3):730-735. https://doi.org/10.1016/0006-291X(84)91455-4
Plesko, Marguerite M. ; Richardson, Arlan. / Age-related changes in unscheduled DNA synthesis by rat hepatocytes. In: Biochemical and Biophysical Research Communications. 1984 ; Vol. 118, No. 3. pp. 730-735.
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