TY - JOUR
T1 - Age-related changes in unscheduled DNA synthesis by rat hepatocytes
AU - Plesko, Marguerite M.
AU - Richardson, Arlan
PY - 1984/2/14
Y1 - 1984/2/14
N2 - Ultraviolet-induced unscheduled DNA synthesis was studied as a function of age in hepatocytes isolated from 6- to 32-months-old rats. Unscheduled DNA synthesis was measured by both DNA specific activity and autoradiography. Using both procedures, a significant decline in unscheduled DNA synthesis was observed after 14 months of age.
AB - Ultraviolet-induced unscheduled DNA synthesis was studied as a function of age in hepatocytes isolated from 6- to 32-months-old rats. Unscheduled DNA synthesis was measured by both DNA specific activity and autoradiography. Using both procedures, a significant decline in unscheduled DNA synthesis was observed after 14 months of age.
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U2 - 10.1016/0006-291X(84)91455-4
DO - 10.1016/0006-291X(84)91455-4
M3 - Article
C2 - 6704104
AN - SCOPUS:0021342558
VL - 118
SP - 730
EP - 735
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
SN - 0006-291X
IS - 3
ER -