Age-related changes in the corneal endothelium of the rat

K. L. Fitch, M. J. Nadakavukaren, A. Richardson

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The endothelial cells of the rat cornea show a progressive decline in numbers and an increase in pleomorphism from age 6 months to 30 months. These age-related changes correspond closely to those reported in the human cornea from approximately age 20 to age 70 years. The corneal endothelium may be found useful as an index of physiological aging in these and other mammals.

Original languageEnglish (US)
Pages (from-to)179-183
Number of pages5
JournalExperimental Gerontology
Volume17
Issue number3
DOIs
StatePublished - 1982
Externally publishedYes

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Corneal Endothelium
Mammals
Endothelial cells
Cornea
Rats
Aging of materials
Endothelial Cells

ASJC Scopus subject areas

  • Aging
  • Medicine(all)

Cite this

Age-related changes in the corneal endothelium of the rat. / Fitch, K. L.; Nadakavukaren, M. J.; Richardson, A.

In: Experimental Gerontology, Vol. 17, No. 3, 1982, p. 179-183.

Research output: Contribution to journalArticle

Fitch, KL, Nadakavukaren, MJ & Richardson, A 1982, 'Age-related changes in the corneal endothelium of the rat', Experimental Gerontology, vol. 17, no. 3, pp. 179-183. https://doi.org/10.1016/0531-5565(82)90023-7
Fitch, K. L. ; Nadakavukaren, M. J. ; Richardson, A. / Age-related changes in the corneal endothelium of the rat. In: Experimental Gerontology. 1982 ; Vol. 17, No. 3. pp. 179-183.
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