Abstract
Comparisons were made with age on phagocytosis, chemotaxis, and esterase staining of autoimmune-resistant and autoimmune-susceptible mouse strains. Consistent increases of each parameter occurred with age. Autoimmune strains generally showed less change with age than autoimmune-resistant mice and the changes with aging were less consistent These findings suggest that phagocytic cells may play an important role in the autoimmunities or the lymphoproliferative processes that occur in autoimmune-prone mice and/or in loss of immune function with aging.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 321-329 |
| Number of pages | 9 |
| Journal | Cellular Immunology |
| Volume | 83 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1984 |
ASJC Scopus subject areas
- Immunology
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Wustrow, T. P. U., Denny, T. N., Fernandes, G., & Good, R. A. (1984). Age-dependent alterations of peritoneal exudate macrophages in autoimmune-prone and autoimmune-resistant mouse strains. Cellular Immunology, 83(2), 321-329. https://doi.org/10.1016/0008-8749(84)90311-3