Adverse Consequences of the 50% Misconception

William B. Kannel, Ramachandran S. Vasan

Research output: Contribution to journalComment/debatepeer-review

17 Scopus citations


It is often claimed that only 50% of the incidence of coronary artery disease in the population can be attributed to the standard major risk factors. A careful review of published research demonstrates that 75% to 90% of coronary artery disease incidence in a variety of populations is explained by the standard modifiable risk factors. In conclusion, these data suggest that a more rigorous focus on these conventional risk factors and the lifestyle behaviors that promote them has great potential to reduce the burden of coronary artery disease worldwide.

Original languageEnglish (US)
Pages (from-to)426-427
Number of pages2
JournalAmerican Journal of Cardiology
Issue number3
StatePublished - Feb 1 2009
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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