Abstract
This questionnaire-based study assessed the understanding and perceptions of cancer patients who were participating in a Phase I clinical trial at baseline and determined any changes after enrollment. Thirty-six patients participated. Less than one-third of respondents (28.5%) thought the purpose of Phase I trials was dose escalation for safety and efficacy. Patients anticipated varying degree of therapeutic benefit ranging from stable disease (47.1%) to complete shrinkage of the tumor (32.4%). No change in measured themes was observed. Patients participating in Phase I trials need further education to improve their understanding of the true intent of early Phase trials.
Original language | English (US) |
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Pages (from-to) | 490-495 |
Number of pages | 6 |
Journal | Cancer Investigation |
Volume | 33 |
Issue number | 10 |
DOIs | |
State | Published - Nov 26 2015 |
Keywords
- Chemotherapy
- Clinical trials
- Medical ethics
ASJC Scopus subject areas
- Cancer Research
- Oncology