Adrenomedullary function in depressed patients

James W. Maas, Martin M. Katz, Stephen H. Koslow, Alan Swann, John M. Davis, Nancy Berman, Charles L. Bowden, Peter E. Stokes, Harold Landis

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


In this paper from the Collaborative Depression Study (CDS)-Biological, a set of data analyses are presented which indicate that depressed states and perhaps depressed mood are associated with a greater activation of the adrenomedullary system than the sympathetic nervous system [as measured by norepinephrine (NE) and normetanephrine excretion]. For the most part this finding of predominant activation of the adrenomedullary system is seen in unipolar and not bipolar patients.

Original languageEnglish (US)
Pages (from-to)357-367
Number of pages11
JournalJournal of Psychiatric Research
Issue number4
StatePublished - 1994

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry


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