Adrenergic receptors in rat spinal cord

D. J. Jones, D. E. Kendall, S. J. Enna

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Radioligand binding assays were used to demonstrate the presence of α1, α(2) and β receptora in rat spinal cord. Specific and saturable binding was exhibited for [3H-WB 4101 (α1), [3H]-aminoclonldine (α2) and [3H]-dihydroalprenolol(β). Binding was of high affinity and the total number of binding sites (Bmaxwere: α1, 66.5 ± 1.0 fmol/mg protein; α2, 20.0 ± 0.6 fmol/mg protein; β, 10.2 ± 0.3 fmol/mg protein. The data confirms the existence of adrenergic receptors in spinal cord and provides further evidence of the role of catecholaminergic neurons in regulating spinal cord physiology.

Original languageEnglish (US)
Pages (from-to)191-195
Number of pages5
Issue number2
StatePublished - Feb 1982

ASJC Scopus subject areas

  • Pharmacology
  • Cellular and Molecular Neuroscience


Dive into the research topics of 'Adrenergic receptors in rat spinal cord'. Together they form a unique fingerprint.

Cite this