Administering riastap for congenital afibrinogenemia during liver transplant

Chris Giordano, Chris Johnson, Janice Lawson, Anita Rajasekhar, Elizabeth Thomas

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Liver transplant has occasionally been performed in the presence of congenital afibrinogenemia and has been rarely used to treat it. Historically, to safely manage coagulopathy during transplant, these patients have been administered a combination of fresh frozen plasma and cryoprecipitate. In this case report, we discuss the first reported use of recombinant fibrinogen to treat such a patient and the decision-making process considered to balance the thrombotic and hemorrhagic risks.

Original languageEnglish (US)
Pages (from-to)269-272
Number of pages4
JournalExperimental and Clinical Transplantation
Volume19
Issue number3
DOIs
StatePublished - 2021
Externally publishedYes

Keywords

  • Coagulopathy
  • Hepatocellular carcinoma
  • Recombinant fibrinogen
  • Thrombosis

ASJC Scopus subject areas

  • Transplantation

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