Abstract
An association between primary headaches and attention-deficit/hyperactivity disorder (ADHD) has long been suggested. Moreover, headache is regarded as a common side effect of stimulants, the most effective treatment for ADHD. So far, no systematic review has evaluated the potential association between ADHD and headache. We performed a systematic review of the literature and a meta-analysis of all reported studies on ADHD and primary headaches. Our analysis showed a positive association between ADHD and migraine (OR 1.322, 95% CI 1.018–1717, p value 0.036), but not with tension-type headache. There is a significant association between migraine and ADHD. The mechanisms underlying this association remain to be elucidated, warranting further studies.
Original language | English (US) |
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Pages (from-to) | 267-277 |
Number of pages | 11 |
Journal | European Child and Adolescent Psychiatry |
Volume | 27 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1 2018 |
Externally published | Yes |
Keywords
- ADHD
- Headache
- Meta-analysis
- Migraine
- Stimulants
- Tension-type headache
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Developmental and Educational Psychology
- Psychiatry and Mental health