Adenomyosis in the baboon is associated with primary infertility

Breton F. Barrier, Marshall J. Malinowski, Edward J. Dick, Gene B. Hubbard, G. Wright Bates

Research output: Contribution to journalArticle

59 Scopus citations

Abstract

To determine whether an association exists between the histopathologic diagnosis of adenomyosis and infertility in a population of captive baboons. Case-control study. Southwest National Primate Research Center. Necropsy records of 37 baboons diagnosed with adenomyosis uteri and 38 baboons with normal uterine histology. None. χ 2 analysis of the association between adenomyosis, primary infertility, and the presence of coexisting endometriosis. Endometriosis was associated with the presence of adenomyosis (OR = 31.5, 95% CI 4.2-1,348). There was a trend toward an association of endometriosis with the presence of lifelong infertility, but this correlation did not quite achieve statistical significance (OR = 3.6, 95% CI 0.9-15.8). Adenomyosis was associated with the presence of lifelong infertility (OR = 20.6, 95% CI 2.7-897). This association was maintained when cases of coexisting endometriosis (n = 17) were excluded (OR = 20.1, 95% CI 2.1-921). Adenomyosis is strongly associated with lifelong primary infertility in the baboon, even in the absence of coexisting endometriosis.

Original languageEnglish (US)
Pages (from-to)1091-1094
Number of pages4
JournalFertility and sterility
Volume82
Issue numberSUPPL. 3
DOIs
StatePublished - Oct 1 2004
Externally publishedYes

Keywords

  • Adenomyosis
  • baboon
  • endometriosis
  • infertility

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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