Adenine phosphoribosyl transferase polymorphism in baboons

John L. VandeBerg, Mary Jo Aivaliotis

    Research output: Contribution to journalArticle

    Abstract

    Two allelic isozymes of adenine phosphoribosyl transferase (APRT) were detected by starch gel electrophoresis of baboon hemolysates. Extensive family data verified autosomal codominant inheritance. The gene frequencies of five subspecies of baboons differed significantly. The activity of erythrocyte APRT is sufficiently high to enable the use of this enzyme as a sensitive marker for assessing chimerism in research involving bone marrow transplantation.

    Original languageEnglish (US)
    Pages (from-to)331-337
    Number of pages7
    JournalBiochemical Genetics
    Volume30
    Issue number7-8
    DOIs
    Publication statusPublished - Aug 1 1992

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    Keywords

    • bone marrow transplantation
    • genetic marker
    • isozyme
    • paternity testing
    • primates

    ASJC Scopus subject areas

    • Ecology, Evolution, Behavior and Systematics
    • Biochemistry
    • Molecular Biology
    • Genetics

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