Adenine phosphoribosyl transferase polymorphism in baboons

John L. VandeBerg; Mary Jo Aivaliotis

doi:10.1007/BF00569323

Adenine phosphoribosyl transferase polymorphism in baboons

John L. VandeBerg, Mary Jo Aivaliotis

Research output: Contribution to journal › Article › peer-review

Abstract

Two allelic isozymes of adenine phosphoribosyl transferase (APRT) were detected by starch gel electrophoresis of baboon hemolysates. Extensive family data verified autosomal codominant inheritance. The gene frequencies of five subspecies of baboons differed significantly. The activity of erythrocyte APRT is sufficiently high to enable the use of this enzyme as a sensitive marker for assessing chimerism in research involving bone marrow transplantation.

Original language	English (US)
Pages (from-to)	331-337
Number of pages	7
Journal	Biochemical Genetics
Volume	30
Issue number	7-8
DOIs	https://doi.org/10.1007/BF00569323
State	Published - Aug 1992

Keywords

bone marrow transplantation
genetic marker
isozyme
paternity testing
primates

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Biochemistry
Molecular Biology
Genetics

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10.1007/BF00569323

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title = "Adenine phosphoribosyl transferase polymorphism in baboons",

abstract = "Two allelic isozymes of adenine phosphoribosyl transferase (APRT) were detected by starch gel electrophoresis of baboon hemolysates. Extensive family data verified autosomal codominant inheritance. The gene frequencies of five subspecies of baboons differed significantly. The activity of erythrocyte APRT is sufficiently high to enable the use of this enzyme as a sensitive marker for assessing chimerism in research involving bone marrow transplantation.",

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author = "VandeBerg, {John L.} and Aivaliotis, {Mary Jo}",

year = "1992",

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doi = "10.1007/BF00569323",

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AU - Aivaliotis, Mary Jo

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AB - Two allelic isozymes of adenine phosphoribosyl transferase (APRT) were detected by starch gel electrophoresis of baboon hemolysates. Extensive family data verified autosomal codominant inheritance. The gene frequencies of five subspecies of baboons differed significantly. The activity of erythrocyte APRT is sufficiently high to enable the use of this enzyme as a sensitive marker for assessing chimerism in research involving bone marrow transplantation.

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KW - genetic marker

KW - isozyme

KW - paternity testing

KW - primates

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Adenine phosphoribosyl transferase polymorphism in baboons

Abstract

Keywords

ASJC Scopus subject areas

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