Acyclovir prophylaxis for oral herpes simplex virus infection in patients with bone marrow transplants

Spencer W. Redding; Michael T. Montgomery

doi:10.1016/0030-4220(89)90008-X

Acyclovir prophylaxis for oral herpes simplex virus infection in patients with bone marrow transplants

Spencer W. Redding, Michael T. Montgomery

Medicine

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Reactivation of herpes simplex virus (HSV) appears to play a significant role in oral mucositis resulting from bone marrow transplantation. The acyclic guanosine derivative acyclovir has been shown to be effective in treating and protecting against HSV infection in this group. The purpose of this study was to determine the role of HSV reactivation in oral mucositis in patients undergoing bone marrow transplantation who were seronegative for HSV or who received acyclovir prophylaxis. The results suggest that HSV plays an insignificant role in oral mucositis in these patients.

Original language	English (US)
Pages (from-to)	680-683
Number of pages	4
Journal	Oral Surgery, Oral Medicine, Oral Pathology
Volume	67
Issue number	6
DOIs	https://doi.org/10.1016/0030-4220(89)90008-X
State	Published - Jun 1989

ASJC Scopus subject areas

Pathology and Forensic Medicine
Dentistry(all)

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10.1016/0030-4220(89)90008-X

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title = "Acyclovir prophylaxis for oral herpes simplex virus infection in patients with bone marrow transplants",

abstract = "Reactivation of herpes simplex virus (HSV) appears to play a significant role in oral mucositis resulting from bone marrow transplantation. The acyclic guanosine derivative acyclovir has been shown to be effective in treating and protecting against HSV infection in this group. The purpose of this study was to determine the role of HSV reactivation in oral mucositis in patients undergoing bone marrow transplantation who were seronegative for HSV or who received acyclovir prophylaxis. The results suggest that HSV plays an insignificant role in oral mucositis in these patients.",

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year = "1989",

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AU - Redding, Spencer W.

AU - Montgomery, Michael T.

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N2 - Reactivation of herpes simplex virus (HSV) appears to play a significant role in oral mucositis resulting from bone marrow transplantation. The acyclic guanosine derivative acyclovir has been shown to be effective in treating and protecting against HSV infection in this group. The purpose of this study was to determine the role of HSV reactivation in oral mucositis in patients undergoing bone marrow transplantation who were seronegative for HSV or who received acyclovir prophylaxis. The results suggest that HSV plays an insignificant role in oral mucositis in these patients.

AB - Reactivation of herpes simplex virus (HSV) appears to play a significant role in oral mucositis resulting from bone marrow transplantation. The acyclic guanosine derivative acyclovir has been shown to be effective in treating and protecting against HSV infection in this group. The purpose of this study was to determine the role of HSV reactivation in oral mucositis in patients undergoing bone marrow transplantation who were seronegative for HSV or who received acyclovir prophylaxis. The results suggest that HSV plays an insignificant role in oral mucositis in these patients.

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JF - Oral Surgery Oral Medicine and Oral Pathology

SN - 2212-4403

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Acyclovir prophylaxis for oral herpes simplex virus infection in patients with bone marrow transplants

Abstract

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