Acute Renal Failure without Oliguria

Christos P. Carvounis, Leon G. Fine, E. N. Wardle, Robert L. Winer, Robert J. Anderson, Arnold S. Berns, Thomas R. Miller, Robert W. Schrier, Stuart L. Linas, William L. Henrich, Patricia A. Gabow

    Research output: Contribution to journalLetterpeer-review


    To the Editor: In reading the article of Anderson et al. (N Engl J Med 296:1134, 1977) on nonoliguric acute renal failure (ARF) I was surprised by the marked heterogeneity of their oliguric patients. In these oliguric patients the U/P creatinine was 16.5±3 (S.E.M.). For n = 24 patients a standard deviation of 14.1 may be calculated. It is apparent from this figure that the values of U/P creatinine must have been substantially skewed, with many greater than 30. The U/P creatinine ratio has been successfully used as a marker to differentiate prerenal azotemia from that of acute renal failure,.

    Original languageEnglish (US)
    Pages (from-to)281-282
    Number of pages2
    JournalNew England Journal of Medicine
    Issue number5
    StatePublished - Aug 4 1977

    ASJC Scopus subject areas

    • General Medicine


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