Acute leukopenia associated with silver sulfadiazine therapy

Philip Valente, Judith L. Axelrod

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

A patient with a 30% scald burn was treated with topical silver sulfadiazine (Silvadene®). On two occasions, within 48 hours of treatment, the patient developed acute leukopenia. Bone marrow aspiration revealed cell maturation arrest. The possible mechanisms of this leukopenia are discussed. It is recommended that daily leukocyte counts be done in burn patients being treated with silver sulfadiazine.

Original languageEnglish (US)
Pages (from-to)146-147
Number of pages2
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume18
Issue number2
DOIs
StatePublished - Feb 1978
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Critical Care and Intensive Care Medicine

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