A patient with a 30% scald burn was treated with topical silver sulfadiazine (Silvadene®). On two occasions, within 48 hours of treatment, the patient developed acute leukopenia. Bone marrow aspiration revealed cell maturation arrest. The possible mechanisms of this leukopenia are discussed. It is recommended that daily leukocyte counts be done in burn patients being treated with silver sulfadiazine.
|Original language||English (US)|
|Number of pages||2|
|Journal||Journal of Trauma - Injury, Infection and Critical Care|
|State||Published - Feb 1978|
ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine