Acute Ischemic Stroke Presentation, Natural History, and Treatment

Sujani Bandela; Aaisha S. Mozumder; Lee A. Birnbaum

doi:10.1007/978-3-030-88196-2_10

Acute Ischemic Stroke Presentation, Natural History, and Treatment

Sujani Bandela, Aaisha S. Mozumder, Lee A. Birnbaum

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Acute ischemic stroke presents with various neurological manifestations that necessitate different emergent care pathways. Intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) for acute ischemic stroke are being utilized more widely as a result of public awareness and expansion of clinical services with tele-stroke. Large vessel occlusion (LVO) stroke is being treated more expeditiously due to prehospital stroke severity assessments that enable EMS bypass protocols and Thrombectomy-Capable Centers that minimize EMS bypass travel times. Although MT has proven efficacy, IVT remains an important treatment for LVO, especially in drip-and-ship models. In addition to acute therapies, this chapter highlights common stroke syndrome presentations and outcomes, landmark clinical trials, neuroimaging modalities, and future directions.

Original language	English (US)
Title of host publication	Introduction to Vascular Neurosurgery
Publisher	Springer International Publishing
Pages	201-213
Number of pages	13
ISBN (Electronic)	9783030881962
ISBN (Print)	9783030881955
DOIs	https://doi.org/10.1007/978-3-030-88196-2_10
State	Published - Jan 1 2022

Keywords

Advanced neuroimaging
Door-in-door-out
Intravenous thrombolysis
Large vessel occlusion
Mechanical thrombectomy
Prehospital stroke severity assessments
Tenecteplase

ASJC Scopus subject areas

General Medicine

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10.1007/978-3-030-88196-2_10

Cite this

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abstract = "Acute ischemic stroke presents with various neurological manifestations that necessitate different emergent care pathways. Intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) for acute ischemic stroke are being utilized more widely as a result of public awareness and expansion of clinical services with tele-stroke. Large vessel occlusion (LVO) stroke is being treated more expeditiously due to prehospital stroke severity assessments that enable EMS bypass protocols and Thrombectomy-Capable Centers that minimize EMS bypass travel times. Although MT has proven efficacy, IVT remains an important treatment for LVO, especially in drip-and-ship models. In addition to acute therapies, this chapter highlights common stroke syndrome presentations and outcomes, landmark clinical trials, neuroimaging modalities, and future directions.",

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N2 - Acute ischemic stroke presents with various neurological manifestations that necessitate different emergent care pathways. Intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) for acute ischemic stroke are being utilized more widely as a result of public awareness and expansion of clinical services with tele-stroke. Large vessel occlusion (LVO) stroke is being treated more expeditiously due to prehospital stroke severity assessments that enable EMS bypass protocols and Thrombectomy-Capable Centers that minimize EMS bypass travel times. Although MT has proven efficacy, IVT remains an important treatment for LVO, especially in drip-and-ship models. In addition to acute therapies, this chapter highlights common stroke syndrome presentations and outcomes, landmark clinical trials, neuroimaging modalities, and future directions.

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Acute Ischemic Stroke Presentation, Natural History, and Treatment

Abstract

Keywords

ASJC Scopus subject areas

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