Abstract
Antioxidant defences are essential for cellular redox regulation. Since free-radical production may be enhanced by physical activity, herein, we evaluated the effect of acute exercise on total antioxidant status (TAS) and the plasma activities of catalase, glutathione reductase, glutathione peroxidase, and superoxide dismutase and its possible relation to oxidative stress resulting from exercise. Healthy untrained male subjects (n = 34) performed three cycloergometric tests, including maximal and submaximal episodes. Venous blood samples were collected before and immediately after each different exercise. TAS and enzyme activities were assessed by spectrophotometry. An increase of the antioxidant enzyme activities in plasma was detected after both maximal and submaximal exercise periods. Moreover, under our experimental conditions, exercise also led to an augmentation of TAS levels. These findings are consistent with the idea that acute exercise may play a beneficial role because of its ability to increase antioxidant defense mechanisms through a redox sensitive pathway.
| Original language | English (US) |
|---|---|
| Article number | 540458 |
| Journal | Journal of Biomedicine and Biotechnology |
| Volume | 2011 |
| DOIs | |
| State | Published - 2011 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biotechnology
- Molecular Medicine
- Genetics
- Molecular Biology
- Health, Toxicology and Mutagenesis
- Medicine(all)
Cite this
Acute exercise increases plasma total antioxidant status and antioxidant enzyme activities in untrained men. / García, J. J.; Berzosa, C.; Cebrián, I.; Fuentes-Broto, L.; Gómez-Trullén, E.; Piedrafita, E.; Martínez-Ballarín, E.; López-Pingarrn, L.; Reiter, Russel J.
In: Journal of Biomedicine and Biotechnology, Vol. 2011, 540458, 2011.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acute exercise increases plasma total antioxidant status and antioxidant enzyme activities in untrained men
AU - García, J. J.
AU - Berzosa, C.
AU - Cebrián, I.
AU - Fuentes-Broto, L.
AU - Gómez-Trullén, E.
AU - Piedrafita, E.
AU - Martínez-Ballarín, E.
AU - López-Pingarrn, L.
AU - Reiter, Russel J
PY - 2011
Y1 - 2011
N2 - Antioxidant defences are essential for cellular redox regulation. Since free-radical production may be enhanced by physical activity, herein, we evaluated the effect of acute exercise on total antioxidant status (TAS) and the plasma activities of catalase, glutathione reductase, glutathione peroxidase, and superoxide dismutase and its possible relation to oxidative stress resulting from exercise. Healthy untrained male subjects (n = 34) performed three cycloergometric tests, including maximal and submaximal episodes. Venous blood samples were collected before and immediately after each different exercise. TAS and enzyme activities were assessed by spectrophotometry. An increase of the antioxidant enzyme activities in plasma was detected after both maximal and submaximal exercise periods. Moreover, under our experimental conditions, exercise also led to an augmentation of TAS levels. These findings are consistent with the idea that acute exercise may play a beneficial role because of its ability to increase antioxidant defense mechanisms through a redox sensitive pathway.
AB - Antioxidant defences are essential for cellular redox regulation. Since free-radical production may be enhanced by physical activity, herein, we evaluated the effect of acute exercise on total antioxidant status (TAS) and the plasma activities of catalase, glutathione reductase, glutathione peroxidase, and superoxide dismutase and its possible relation to oxidative stress resulting from exercise. Healthy untrained male subjects (n = 34) performed three cycloergometric tests, including maximal and submaximal episodes. Venous blood samples were collected before and immediately after each different exercise. TAS and enzyme activities were assessed by spectrophotometry. An increase of the antioxidant enzyme activities in plasma was detected after both maximal and submaximal exercise periods. Moreover, under our experimental conditions, exercise also led to an augmentation of TAS levels. These findings are consistent with the idea that acute exercise may play a beneficial role because of its ability to increase antioxidant defense mechanisms through a redox sensitive pathway.
UR - http://www.scopus.com/inward/record.url?scp=79955015665&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79955015665&partnerID=8YFLogxK
U2 - 10.1155/2011/540458
DO - 10.1155/2011/540458
M3 - Article
VL - 2011
JO - BioMed Research International
JF - BioMed Research International
SN - 2314-6133
M1 - 540458
ER -