Acute Duodenitis and Duodenal Ulceration After Burns: Clinical and Pathological Characteristics

Albert J. Czaja, Joseph C. McAlhany, Basil A. Pruitt

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


The clinical and pathological characteristics of Curling ulcer were defined by early and serial endoscopic examinations of the duodenum in 37 burned patients. Duodenal disease was present in 27 patients and occurred only in patients with burns involving more than 38% of the total body surface. Erosive “duodenitis” could occur within 12 hours after injury and was usually associated with acute gastric disease. Isolated duodenitis occurred only in patients with pancreatitis. Contrast roentgenograms did not reliably show the superficial mucosal disease. Duodenal ulcerations were present in 12 patients and developed on a background of diffuse superficial mucosal injury. Other complications in the patient's postburn course influenced disease progression. Hemorrhage occurred in six patients with duodenal disease, usually originating from a posterior duodenal ulcer. Uncomplicated ulcers invariably healed within five weeks after diagnosis.

Original languageEnglish (US)
Pages (from-to)621-624
Number of pages4
JournalJAMA: The Journal of the American Medical Association
Issue number6
StatePublished - May 12 1975

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Acute Duodenitis and Duodenal Ulceration After Burns: Clinical and Pathological Characteristics'. Together they form a unique fingerprint.

Cite this