Activity of the diaminopyrimidine AR-709 against recently collected multidrug-resistant isolates of invasive Streptococcus pneumoniae from North America

Roseanne A. Ressner, Matthew R. Moore, James H. Jorgensen

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Broth microdilution was used to determine the MICs of AR-709 and comparator antimicrobial agents for 224 invasive multidrug-resistant isolates of Streptococcus pneumoniae. AR-709 was highly active, with a MIC50 of 0.25 μg/ml, a MIC90 of 0.5 μg/ml, and a range of ≤0.008 μg/ml to 1 μg/ml.

Original languageEnglish (US)
Pages (from-to)1147-1149
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume52
Issue number3
DOIs
StatePublished - Mar 2008

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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