Abstract
The susceptibilities of a group of penicillinase-producing and none-penicillinase-producing isolates of Neisseria gonorrhoeae were determined to the monobactam aztreonam, four third-generation cephalosporins, and three second-generation cephalosporins. Aztreonam and the third-generation cephalosporins were highly active against both penicillin-resistant and penicillin-susceptible strains. MIC90s for penicillin-resistant isolates were the same as or not more than fourfold higher than for penicillin-susceptible strains. Ceftizoxime and defotaxime were the most active of the compounds tested; aztreonam, deftrazidime, moxalactam, and defuroxime were somewhate less active and had activities similar to another. Cefoxitin and cefamandole were the least active antibiotics tested.
Original language | English (US) |
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Pages (from-to) | 955-959 |
Number of pages | 5 |
Journal | Current Therapeutic Research - Clinical and Experimental |
Volume | 34 |
Issue number | 6 |
State | Published - Jan 1 1983 |
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)