Activities of amphotericin B and antifungal azoles alone and in combination against Pseudallescheria boydii

T. J. Walsh; J. Peter; D. A. McGough; A. W. Fothergill; M. G. Rinaldi; P. A. Pizzo

doi:10.1128/AAC.39.6.1361

Activities of amphotericin B and antifungal azoles alone and in combination against Pseudallescheria boydii

T. J. Walsh, J. Peter, D. A. McGough, A. W. Fothergill, M. G. Rinaldi, P. A. Pizzo

Pathology

Research output: Contribution to journal › Comment/debate › peer-review

106 Scopus citations

Abstract

In order to develop new approaches to treatment of infections due to Pseudallescheria boydii, the in vitro antifungal activity of amphotericin B alone and in combination with miconazole, itraconazole, and fluconazole was studied. Combinations of amphotericin B and antifungal azoles were synergistic, additive, or indifferent in their interaction against P. boydii. Antagonism was not observed.

Original language	English (US)
Pages (from-to)	1361-1364
Number of pages	4
Journal	Antimicrobial agents and chemotherapy
Volume	39
Issue number	6
DOIs	https://doi.org/10.1128/AAC.39.6.1361
State	Published - 1995

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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title = "Activities of amphotericin B and antifungal azoles alone and in combination against Pseudallescheria boydii",

abstract = "In order to develop new approaches to treatment of infections due to Pseudallescheria boydii, the in vitro antifungal activity of amphotericin B alone and in combination with miconazole, itraconazole, and fluconazole was studied. Combinations of amphotericin B and antifungal azoles were synergistic, additive, or indifferent in their interaction against P. boydii. Antagonism was not observed.",

author = "Walsh, {T. J.} and J. Peter and McGough, {D. A.} and Fothergill, {A. W.} and Rinaldi, {M. G.} and Pizzo, {P. A.}",

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AU - Walsh, T. J.

AU - Peter, J.

AU - McGough, D. A.

AU - Fothergill, A. W.

AU - Rinaldi, M. G.

AU - Pizzo, P. A.

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AB - In order to develop new approaches to treatment of infections due to Pseudallescheria boydii, the in vitro antifungal activity of amphotericin B alone and in combination with miconazole, itraconazole, and fluconazole was studied. Combinations of amphotericin B and antifungal azoles were synergistic, additive, or indifferent in their interaction against P. boydii. Antagonism was not observed.

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