Activities of amphotericin B and antifungal azoles alone and in combination against Pseudallescheria boydii

T. J. Walsh, J. Peter, D. A. McGough, A. W. Fothergill, M. G. Rinaldi, P. A. Pizzo

Research output: Contribution to journalComment/debate

106 Scopus citations

Abstract

In order to develop new approaches to treatment of infections due to Pseudallescheria boydii, the in vitro antifungal activity of amphotericin B alone and in combination with miconazole, itraconazole, and fluconazole was studied. Combinations of amphotericin B and antifungal azoles were synergistic, additive, or indifferent in their interaction against P. boydii. Antagonism was not observed.

Original languageEnglish (US)
Pages (from-to)1361-1364
Number of pages4
JournalAntimicrobial agents and chemotherapy
Volume39
Issue number6
DOIs
StatePublished - 1995

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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    Walsh, T. J., Peter, J., McGough, D. A., Fothergill, A. W., Rinaldi, M. G., & Pizzo, P. A. (1995). Activities of amphotericin B and antifungal azoles alone and in combination against Pseudallescheria boydii. Antimicrobial agents and chemotherapy, 39(6), 1361-1364. https://doi.org/10.1128/AAC.39.6.1361