Acetate Dialysate Versus Bicarbonate Dialysate: A Continuing Controversy

Susan M. Diamond, William L. Henrich

Research output: Contribution to journalReview articlepeer-review

49 Scopus citations


The use of bicarbonate dialysate as the buffer during routine dialysis is growing. This discussion reviews several of the comparative trials in which bicarbonate and acetate buffers have been tested. Effects of the two buffers on BP, cardiac function, and pulmonary performance are discussed. Costs of the two systems are also compared. Patients who seem most likely to benefit from bicarbonate dialysate include those with a reduced muscle mass in whom a high sodium dialysate has not prevented hypotension.

Original languageEnglish (US)
Pages (from-to)3-11
Number of pages9
JournalAmerican Journal of Kidney Diseases
Issue number1
StatePublished - 1987


  • Dialysate buffer
  • acetate dialysis
  • bicarbonate dialysis
  • dialysis
  • hypotension

ASJC Scopus subject areas

  • Nephrology


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