TY - JOUR
T1 - Accuracy of the 15-item geriatric depression scale (GDS-15) in a community-dwelling oldest-old sample
T2 - The pietà study
AU - Dias, Filipi Leles da Costa
AU - Teixeira, Antônio Lúcio
AU - Guimarães, Henrique Cerqueira
AU - Barbosa, Maira Tonidandel
AU - Resende, Elisa de Paula França
AU - Beato, Rogério Gomes
AU - Carmona, Karoline Carvalho
AU - Caramelli, Paulo
N1 - Publisher Copyright:
© 2017, Sociedade de Psiquiatria do Rio Grande do Sul. All rights reserved.
PY - 2017/10/1
Y1 - 2017/10/1
N2 - Introduction: Late-life depression (LLD) is common, but remains underdiagnosed. Validated screening tools for use with the oldest-old in clinical practice are still lacking, particularly in developing countries. Objectives: To evaluate the accuracy of a screening tool for LLD in a community-dwelling oldest-old sample. Methods: We evaluated 457 community-dwelling elderly subjects, aged ≥75 years and without dementia, with the Geriatric Depression Scale (GDS-15). Depression diagnosis was established according to DSM-IV criteria following a structured psychiatric interview with the Mini International Neuropsychiatric Interview (MINI). Results: Fifty-two individuals (11.4%) were diagnosed with major depression. The area under the receiver operating characteristic (ROC) curve was 0.908 (p<0.001). Using a cut-off score of 5/6 (not depressed/depressed), 84 (18.4%) subjects were considered depressed by the GDS-15 (kappa coefficient = 53.8%, p<0.001). The 4/5 cut-off point achieved the best combination of sensitivity (86.5%) and specificity (82.7%) (Youden’s index = 0.692), with robust negative (0.9802) and reasonable positive predictive values (0.3819). Conclusion: GDS-15 showed good accuracy as a screening tool for major depression in this community-based sample of low-educated oldest-old individuals. Our findings support the use of the 4/5 cut-off score, which showed the best diagnostic capacity.
AB - Introduction: Late-life depression (LLD) is common, but remains underdiagnosed. Validated screening tools for use with the oldest-old in clinical practice are still lacking, particularly in developing countries. Objectives: To evaluate the accuracy of a screening tool for LLD in a community-dwelling oldest-old sample. Methods: We evaluated 457 community-dwelling elderly subjects, aged ≥75 years and without dementia, with the Geriatric Depression Scale (GDS-15). Depression diagnosis was established according to DSM-IV criteria following a structured psychiatric interview with the Mini International Neuropsychiatric Interview (MINI). Results: Fifty-two individuals (11.4%) were diagnosed with major depression. The area under the receiver operating characteristic (ROC) curve was 0.908 (p<0.001). Using a cut-off score of 5/6 (not depressed/depressed), 84 (18.4%) subjects were considered depressed by the GDS-15 (kappa coefficient = 53.8%, p<0.001). The 4/5 cut-off point achieved the best combination of sensitivity (86.5%) and specificity (82.7%) (Youden’s index = 0.692), with robust negative (0.9802) and reasonable positive predictive values (0.3819). Conclusion: GDS-15 showed good accuracy as a screening tool for major depression in this community-based sample of low-educated oldest-old individuals. Our findings support the use of the 4/5 cut-off score, which showed the best diagnostic capacity.
KW - Depression
KW - Geriatric assessment
KW - Geriatric psychiatry
UR - https://www.scopus.com/pages/publications/85038808226
UR - https://www.scopus.com/pages/publications/85038808226#tab=citedBy
U2 - 10.1590/2237-6089-2017-0046
DO - 10.1590/2237-6089-2017-0046
M3 - Article
C2 - 29267511
AN - SCOPUS:85038808226
SN - 2237-6089
VL - 39
SP - 276
EP - 279
JO - Trends in Psychiatry and Psychotherapy
JF - Trends in Psychiatry and Psychotherapy
IS - 4
ER -