A study of some complement functions was performed in two patients affected with hereditary angioneurotic edema (HAE), mother and daughter, and in three of their relatives. A decreased level of the C1 esterase plasma inhibitor was found in both the patients, who were treated with tranexamic acid with a slight, but definite improvement. However, the disease could not be traced beyond two generations in the pedigree. The possibility that HAE arose in the family through a mutational event is discussed.
|Original language||English (US)|
|Number of pages||4|
|Journal||Bollettino dell'Istituto Sieroterapico Milanese|
|State||Published - Dec 1 1975|
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