A study of complement functions in a family with hereditary angioneurotic edema

P. Casali, C. Rugarli, C. Zanussi

Research output: Contribution to journalArticle


A study of some complement functions was performed in two patients affected with hereditary angioneurotic edema (HAE), mother and daughter, and in three of their relatives. A decreased level of the C1 esterase plasma inhibitor was found in both the patients, who were treated with tranexamic acid with a slight, but definite improvement. However, the disease could not be traced beyond two generations in the pedigree. The possibility that HAE arose in the family through a mutational event is discussed.

Original languageEnglish (US)
Pages (from-to)405-408
Number of pages4
JournalBollettino dell'Istituto Sieroterapico Milanese
Issue number5
StatePublished - Dec 1 1975
Externally publishedYes


ASJC Scopus subject areas

  • Immunology

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