A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity

Sajid Khan, Xuan Zhang, Dongwen Lv, Qi Zhang, Yonghan He, Peiyi Zhang, Xingui Liu, Dinesh Thummuri, Yaxia Yuan, Janet S. Wiegand, Jing Pei, Weizhou Zhang, Abhisheak Sharma, Christopher R. McCurdy, Vinitha M. Kuruvilla, Natalia Baran, Adolfo A. Ferrando, Yong mi Kim, Anna Rogojina, Peter J. HoughtonGuangcun Huang, Robert Hromas, Marina Konopleva, Guangrong Zheng, Daohong Zhou

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Chemical Compounds

Medicine & Life Sciences