A Secular Increase in Child and Adolescent Onset Affective Disorder

NEAL D. RYAN, DOUGLAS E. WILLIAMSON, SATISH IYENGAR, HELEN ORVASCHEL, THEODORE REICH, RONALD E. DAHL, JOAQUIM PUIG-ANTICH

Research output: Contribution to journalArticlepeer-review

95 Scopus citations

Abstract

Both longitudinal and cross-sectional studies utilizing population and family study samples have found evidence for a secular increase in major affective disorders in adults. Applying techniques used in cross-sectional studies in adults to family study data of children and adolescents, the authors demonstrate evidence of a parallel secular increase for child and adolescent onset affective disorders. Normal and depressed prepubertal probands were identified. All full siblings were directly interviewed for lifetime episodes of affective disorder. Analysis of the siblings (probands not further analyzed in this article) by the Cox proportional hazards model demonstrates that the risk for affective disorder is higher in siblings born more recently.

Original languageEnglish (US)
Pages (from-to)600-605
Number of pages6
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume31
Issue number4
DOIs
StatePublished - Jan 1 1992

Keywords

  • child and adolescent affective disorders
  • proportional hazards
  • secular increase

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Psychiatry and Mental health

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