Abstract
Sphingolipidomics, a branch of lipidomics, focuses on the large-scale study of the cellular sphingolipidomes. In the current review, two main approaches for the analysis of cellular sphingolipidomes (i.e. LC-MS-or LC-MS/MS-based approach and shotgun lipidomics-based approach) are briefly discussed. Their advantages, some considerations of these methods, and recent applications of these approaches are summarized. It is the authors' sincere hope that this review article will add to the readers understanding of the advantages and limitations of each developed method for the analysis of a cellular sphingolipidome.
Original language | English (US) |
---|---|
Pages (from-to) | 39-52 |
Number of pages | 14 |
Journal | European Journal of Lipid Science and Technology |
Volume | 111 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2009 |
Externally published | Yes |
Keywords
- Intrasource separation
- Lipidomics
- Multi-dimensional mass spectrometry
- Shotgun lipidomics
- Sphingolipidomics
ASJC Scopus subject areas
- General Chemistry
- Food Science
- Biotechnology
- Industrial and Manufacturing Engineering