A rare case of non-Hodgkins B-cell lymphoma in a psoriatic patient: A case report and literature review

Shilpa Gattu, Emily M. Becker, John Y.M. Koo

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Cyclosporine has been shown to increase the risk of lymphoma when used in organ transplant patients; however, studies have failed to demonstrate an increased risk of lymphoma when used at lower dermatologic doses for psoriasis. The authors present a case of solid B-cell lymphoma occurring in a psoriasis patient with a history of intermittent exposure to high-dose methotrexate, followed by low-dose cyclosporine for two years and subsequently transitioned to treatment with adalimumab. Methotrexate, cyclosporine and adalimumab are each effective treatments for psoriasis. However, when faced with an interplay of several factors, closer surveillance for malignancy is warranted than that which is currently considered for monotherapy.

Original languageEnglish (US)
Pages (from-to)1277-1281
Number of pages5
JournalJournal of Drugs in Dermatology
Volume9
Issue number10
StatePublished - Oct 2010

ASJC Scopus subject areas

  • Dermatology

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