Abstract
The images resulting from cDNA microarrays are highly random. There are many aspects to this randomness, including spot size, shape, intensity, uniformity, and circularity, as well as both foreground and background noise. This paper presents a random model for the generation of microarray images. The model is complicated and contains over twenty parameters. It can be used to test microarray imaging algorithms and to simulate the effects of various dependencies within the image formation process.
Original language | English (US) |
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Pages (from-to) | 163-170 |
Number of pages | 8 |
Journal | Proceedings of SPIE-The International Society for Optical Engineering |
Volume | 4266 |
DOIs | |
State | Published - 2001 |
Externally published | Yes |
Keywords
- Random model
- Simulated cDNA microarray
- cDNA spot model
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering