A quantitative measure for radiation treatment plan quality

Anna Laura Licon, Dewayne Defoor, John Ford, Richard L Crownover, Ying Li, Chul S Ha, Tony Eng, William Jones, Panayiotis Mavroidis, Nikos Papanikolaou, Sotirios Stathakis

Research output: Contribution to journalArticle

Abstract

Purpose: To develop and validate an intensity modulated radiation therapy (IMRT) treatment plan quantitative score using QUANTEC dose/volume parameters to assess plan quality. Methods: 132 IMRT and volumetric modulated Arc therapy (VMAT) patient plans of various treatment sites were evaluated. The optimized plan’s dose volume histogram (DVH) was exported to Velocity for evaluation. The proposed scoring was based on calculating the shortest distance from the QUANTEC objective to the DVH line of each organ. Each plan was normalized against the ideal plan where the organs at risk (OARs) received no dose and hence the distance between the QUANTEC objective and the DVH line was maximized. These normalized scores enabled the comparison of the quality of plans across treatment sites and dosimetrists. The scores were plotted and statistically analyzed to serve as a basis for future research. Results: The score for each treatment site was evaluated and the average percentage scores±SD were found to be 43.5 ± 21.0, 33.3 ± 31.7, 42.6 ± 23.3, 40.2 ± 24.4, 33.5 ± 23.5 for the sites of abdomen, brain, chest, head/neck, and pelvis respectively. Differences in scores between the treatment sites were largely attributed to OAR segmentation and proximity of the OAR to the planning target volume (PTV). Small score differences between dosimetrists were attributed to the number of plans they have completed. Conclusion: This approach allows comparison of patient treatments which will help improve patient care and treatment outcomes. A larger sample of treatment plans is being evaluated to investigate the effect of dosimetrist’s experience on plan quality.

Original languageEnglish (US)
Pages (from-to)1460-1466
Number of pages7
JournalJournal of B.U.ON.
Volume23
Issue number5
StatePublished - Sep 1 2018

Fingerprint

Radiation
Organs at Risk
Therapeutics
Radiotherapy
Intensity-Modulated Radiotherapy
Pelvis
Abdomen
Patient Care
Neck
Thorax
Head
Brain

Keywords

  • DVH
  • Photons
  • Plan evaluation
  • Radiation therapy

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

Cite this

Licon, A. L., Defoor, D., Ford, J., Crownover, R. L., Li, Y., Ha, C. S., ... Stathakis, S. (2018). A quantitative measure for radiation treatment plan quality. Journal of B.U.ON., 23(5), 1460-1466.

A quantitative measure for radiation treatment plan quality. / Licon, Anna Laura; Defoor, Dewayne; Ford, John; Crownover, Richard L; Li, Ying; Ha, Chul S; Eng, Tony; Jones, William; Mavroidis, Panayiotis; Papanikolaou, Nikos; Stathakis, Sotirios.

In: Journal of B.U.ON., Vol. 23, No. 5, 01.09.2018, p. 1460-1466.

Research output: Contribution to journalArticle

Licon, AL, Defoor, D, Ford, J, Crownover, RL, Li, Y, Ha, CS, Eng, T, Jones, W, Mavroidis, P, Papanikolaou, N & Stathakis, S 2018, 'A quantitative measure for radiation treatment plan quality', Journal of B.U.ON., vol. 23, no. 5, pp. 1460-1466.
Licon AL, Defoor D, Ford J, Crownover RL, Li Y, Ha CS et al. A quantitative measure for radiation treatment plan quality. Journal of B.U.ON. 2018 Sep 1;23(5):1460-1466.
Licon, Anna Laura ; Defoor, Dewayne ; Ford, John ; Crownover, Richard L ; Li, Ying ; Ha, Chul S ; Eng, Tony ; Jones, William ; Mavroidis, Panayiotis ; Papanikolaou, Nikos ; Stathakis, Sotirios. / A quantitative measure for radiation treatment plan quality. In: Journal of B.U.ON. 2018 ; Vol. 23, No. 5. pp. 1460-1466.
@article{c1fed239a4cb44e3adbaac67fdb81178,
title = "A quantitative measure for radiation treatment plan quality",
abstract = "Purpose: To develop and validate an intensity modulated radiation therapy (IMRT) treatment plan quantitative score using QUANTEC dose/volume parameters to assess plan quality. Methods: 132 IMRT and volumetric modulated Arc therapy (VMAT) patient plans of various treatment sites were evaluated. The optimized plan’s dose volume histogram (DVH) was exported to Velocity for evaluation. The proposed scoring was based on calculating the shortest distance from the QUANTEC objective to the DVH line of each organ. Each plan was normalized against the ideal plan where the organs at risk (OARs) received no dose and hence the distance between the QUANTEC objective and the DVH line was maximized. These normalized scores enabled the comparison of the quality of plans across treatment sites and dosimetrists. The scores were plotted and statistically analyzed to serve as a basis for future research. Results: The score for each treatment site was evaluated and the average percentage scores±SD were found to be 43.5 ± 21.0, 33.3 ± 31.7, 42.6 ± 23.3, 40.2 ± 24.4, 33.5 ± 23.5 for the sites of abdomen, brain, chest, head/neck, and pelvis respectively. Differences in scores between the treatment sites were largely attributed to OAR segmentation and proximity of the OAR to the planning target volume (PTV). Small score differences between dosimetrists were attributed to the number of plans they have completed. Conclusion: This approach allows comparison of patient treatments which will help improve patient care and treatment outcomes. A larger sample of treatment plans is being evaluated to investigate the effect of dosimetrist’s experience on plan quality.",
keywords = "DVH, Photons, Plan evaluation, Radiation therapy",
author = "Licon, {Anna Laura} and Dewayne Defoor and John Ford and Crownover, {Richard L} and Ying Li and Ha, {Chul S} and Tony Eng and William Jones and Panayiotis Mavroidis and Nikos Papanikolaou and Sotirios Stathakis",
year = "2018",
month = "9",
day = "1",
language = "English (US)",
volume = "23",
pages = "1460--1466",
journal = "Journal of B.U.ON.",
issn = "1107-0625",
publisher = "Balkan Union of Oncology",
number = "5",

}

TY - JOUR

T1 - A quantitative measure for radiation treatment plan quality

AU - Licon, Anna Laura

AU - Defoor, Dewayne

AU - Ford, John

AU - Crownover, Richard L

AU - Li, Ying

AU - Ha, Chul S

AU - Eng, Tony

AU - Jones, William

AU - Mavroidis, Panayiotis

AU - Papanikolaou, Nikos

AU - Stathakis, Sotirios

PY - 2018/9/1

Y1 - 2018/9/1

N2 - Purpose: To develop and validate an intensity modulated radiation therapy (IMRT) treatment plan quantitative score using QUANTEC dose/volume parameters to assess plan quality. Methods: 132 IMRT and volumetric modulated Arc therapy (VMAT) patient plans of various treatment sites were evaluated. The optimized plan’s dose volume histogram (DVH) was exported to Velocity for evaluation. The proposed scoring was based on calculating the shortest distance from the QUANTEC objective to the DVH line of each organ. Each plan was normalized against the ideal plan where the organs at risk (OARs) received no dose and hence the distance between the QUANTEC objective and the DVH line was maximized. These normalized scores enabled the comparison of the quality of plans across treatment sites and dosimetrists. The scores were plotted and statistically analyzed to serve as a basis for future research. Results: The score for each treatment site was evaluated and the average percentage scores±SD were found to be 43.5 ± 21.0, 33.3 ± 31.7, 42.6 ± 23.3, 40.2 ± 24.4, 33.5 ± 23.5 for the sites of abdomen, brain, chest, head/neck, and pelvis respectively. Differences in scores between the treatment sites were largely attributed to OAR segmentation and proximity of the OAR to the planning target volume (PTV). Small score differences between dosimetrists were attributed to the number of plans they have completed. Conclusion: This approach allows comparison of patient treatments which will help improve patient care and treatment outcomes. A larger sample of treatment plans is being evaluated to investigate the effect of dosimetrist’s experience on plan quality.

AB - Purpose: To develop and validate an intensity modulated radiation therapy (IMRT) treatment plan quantitative score using QUANTEC dose/volume parameters to assess plan quality. Methods: 132 IMRT and volumetric modulated Arc therapy (VMAT) patient plans of various treatment sites were evaluated. The optimized plan’s dose volume histogram (DVH) was exported to Velocity for evaluation. The proposed scoring was based on calculating the shortest distance from the QUANTEC objective to the DVH line of each organ. Each plan was normalized against the ideal plan where the organs at risk (OARs) received no dose and hence the distance between the QUANTEC objective and the DVH line was maximized. These normalized scores enabled the comparison of the quality of plans across treatment sites and dosimetrists. The scores were plotted and statistically analyzed to serve as a basis for future research. Results: The score for each treatment site was evaluated and the average percentage scores±SD were found to be 43.5 ± 21.0, 33.3 ± 31.7, 42.6 ± 23.3, 40.2 ± 24.4, 33.5 ± 23.5 for the sites of abdomen, brain, chest, head/neck, and pelvis respectively. Differences in scores between the treatment sites were largely attributed to OAR segmentation and proximity of the OAR to the planning target volume (PTV). Small score differences between dosimetrists were attributed to the number of plans they have completed. Conclusion: This approach allows comparison of patient treatments which will help improve patient care and treatment outcomes. A larger sample of treatment plans is being evaluated to investigate the effect of dosimetrist’s experience on plan quality.

KW - DVH

KW - Photons

KW - Plan evaluation

KW - Radiation therapy

UR - http://www.scopus.com/inward/record.url?scp=85053247696&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85053247696&partnerID=8YFLogxK

M3 - Article

VL - 23

SP - 1460

EP - 1466

JO - Journal of B.U.ON.

JF - Journal of B.U.ON.

SN - 1107-0625

IS - 5

ER -