A Prediction Model for Estimating Pulmonary Oxygen Uptake During the 6-Minute Walk Test in Organ Transplant Recipients

C. R. Tomczak, D. E.R. Warburton, K. J. Riess, N. G. Jendzjowsky, Y. Liang, Y. Bhambhani, R. G. Haennel, M. J. Haykowsky

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

We developed a multivariate prediction equation for estimating the highest obtainable pulmonary oxygen uptake (V̇O2p) during the 6-minute walk test (6-MWT) in 54 organ transplant recipients: heart/heart-double-lung (n = 14), kidney/kidney-pancreas (n = 16), liver (n = 14), double lung (n = 8), bone marrow (n = 2). They were of age, 48 ± 12 years. Participants performed a 6-MWT during which expired gases were collected and analyzed with a portable metabolic system interfaced with a wireless heart rate monitor. The following variables significantly contributed to the model for predicting the highest obtainable 6-MWT V̇O2p: 6-MWT distance (m), age (years), gender (male = 0, female = 1), resting heart rate, peak heart rate, weight (kg), and transplant type (kidney/kidney-pancreas = 1, other = 0), where: V̇O2p = 1.253 + 0.022 (6-MWT distance) + 0.112 (age) -3.192 (gender) -0.104 (resting heart rate) + 0.127 (peak 6-MWT heart rate) - 0.084 (weight) + 2.116 (transplant type). The explanatory variables in our final model accounted for 78% of the variance in 6-MWT V̇O2p. In conclusion, the addition of an easily estimated 6-MWT V̇O2p will provide added clinical information of functional capacity following an exercise rehabilitation intervention or during routine follow-up for organ transplant recipients.

Original languageEnglish (US)
Pages (from-to)3313-3316
Number of pages4
JournalTransplantation Proceedings
Volume39
Issue number10
DOIs
StatePublished - Dec 1 2007
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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