A path forward for the chlamydial virulence factor CPAF

Turner A. Conrad; Zhangsheng Yang; David Ojcius; Guangming Zhong

doi:10.1016/j.micinf.2013.09.008

A path forward for the chlamydial virulence factor CPAF

Turner A. Conrad, Zhangsheng Yang, David Ojcius, Guangming Zhong

Department of Microbiology, Immunology & Molecular Genetics

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

CPAF is a conserved and secreted protease from obligate intracellular bacteria of the order Chlamydiales. Recently, it was demonstrated that most of its host targets are an artifact of inaccurate methods. This review aims to summarize key features of CPAF and propose new approaches for evaluating its role in chlamydial pathogenesis.

Original language	English (US)
Pages (from-to)	1026-1032
Number of pages	7
Journal	Microbes and Infection
Volume	15
Issue number	14-15
DOIs	https://doi.org/10.1016/j.micinf.2013.09.008
State	Published - Dec 2013

Keywords

CPAF
Chlamydial virulence factors and pathogenesis
Substrates

ASJC Scopus subject areas

Microbiology
Immunology
Infectious Diseases

Access to Document

10.1016/j.micinf.2013.09.008

Cite this

@article{bff574f0a47348dca894a84fc0391e74,

title = "A path forward for the chlamydial virulence factor CPAF",

abstract = "CPAF is a conserved and secreted protease from obligate intracellular bacteria of the order Chlamydiales. Recently, it was demonstrated that most of its host targets are an artifact of inaccurate methods. This review aims to summarize key features of CPAF and propose new approaches for evaluating its role in chlamydial pathogenesis.",

keywords = "CPAF, Chlamydial virulence factors and pathogenesis, Substrates",

author = "Conrad, {Turner A.} and Zhangsheng Yang and David Ojcius and Guangming Zhong",

year = "2013",

month = dec,

doi = "10.1016/j.micinf.2013.09.008",

language = "English (US)",

volume = "15",

pages = "1026--1032",

journal = "Microbes and Infection",

issn = "1286-4579",

publisher = "Elsevier Masson s.r.l.",

number = "14-15",

}

TY - JOUR

T1 - A path forward for the chlamydial virulence factor CPAF

AU - Conrad, Turner A.

AU - Yang, Zhangsheng

AU - Ojcius, David

AU - Zhong, Guangming

PY - 2013/12

Y1 - 2013/12

N2 - CPAF is a conserved and secreted protease from obligate intracellular bacteria of the order Chlamydiales. Recently, it was demonstrated that most of its host targets are an artifact of inaccurate methods. This review aims to summarize key features of CPAF and propose new approaches for evaluating its role in chlamydial pathogenesis.

AB - CPAF is a conserved and secreted protease from obligate intracellular bacteria of the order Chlamydiales. Recently, it was demonstrated that most of its host targets are an artifact of inaccurate methods. This review aims to summarize key features of CPAF and propose new approaches for evaluating its role in chlamydial pathogenesis.

KW - CPAF

KW - Chlamydial virulence factors and pathogenesis

KW - Substrates

UR - http://www.scopus.com/inward/record.url?scp=84889094466&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84889094466&partnerID=8YFLogxK

U2 - 10.1016/j.micinf.2013.09.008

DO - 10.1016/j.micinf.2013.09.008

M3 - Article

C2 - 24141088

AN - SCOPUS:84889094466

SN - 1286-4579

VL - 15

SP - 1026

EP - 1032

JO - Microbes and Infection

JF - Microbes and Infection

IS - 14-15

ER -

A path forward for the chlamydial virulence factor CPAF

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this