A path forward for the chlamydial virulence factor CPAF

Turner A. Conrad, Zhangsheng Yang, David Ojcius, Guangming Zhong

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

CPAF is a conserved and secreted protease from obligate intracellular bacteria of the order Chlamydiales. Recently, it was demonstrated that most of its host targets are an artifact of inaccurate methods. This review aims to summarize key features of CPAF and propose new approaches for evaluating its role in chlamydial pathogenesis.

Original languageEnglish (US)
Pages (from-to)1026-1032
Number of pages7
JournalMicrobes and Infection
Volume15
Issue number14-15
DOIs
StatePublished - Dec 1 2013

Keywords

  • CPAF
  • Chlamydial virulence factors and pathogenesis
  • Substrates

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

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