TY - JOUR
T1 - A new suggested strategy for safe injection of ozurdex
AU - Krambeer, Chelsey J.
AU - Wannamaker, Kendall W.
AU - Tie, Wayne
AU - Bahadorani, Sepehr
AU - Singer, Julia
AU - Conston, Stan
AU - Singer, Michael A.
N1 - Publisher Copyright:
© 2019 Krambeer, Wannamaker, Tie, et al.
PY - 2019/2
Y1 - 2019/2
N2 - BACKGROUND AND OBJECTIVES: Ozurdex intravitreal injection is performed via a patented injection device. However, there is a common misconception among ophthalmologists regarding the relation between the speed of applicator button depression and the speed of pellet injection. PATIENTS AND METHODS: Six dexamethasone intravitreal implants were injected into a calibrated ex vivo water bath. Three of the pellets were injected via rapid compression, whereas the other three implants were injected using a 3-second compression technique. The procedures were recorded using high-speed photography followed by calculation of pellet velocity and impact force. RESULTS: The mean impact velocity and force of the pellet insertion is significantly higher in the fast injection group compared to the slow injection group. CONCLUSIONS: By depressing the Ozurdex implant injector during a 3-second time interval, the impact force of the implant pellet is reduced by about 95%. This new technique will theoretically reduce the risk of retinal injury and vitreous hemorrhage from Ozurdex injections.
AB - BACKGROUND AND OBJECTIVES: Ozurdex intravitreal injection is performed via a patented injection device. However, there is a common misconception among ophthalmologists regarding the relation between the speed of applicator button depression and the speed of pellet injection. PATIENTS AND METHODS: Six dexamethasone intravitreal implants were injected into a calibrated ex vivo water bath. Three of the pellets were injected via rapid compression, whereas the other three implants were injected using a 3-second compression technique. The procedures were recorded using high-speed photography followed by calculation of pellet velocity and impact force. RESULTS: The mean impact velocity and force of the pellet insertion is significantly higher in the fast injection group compared to the slow injection group. CONCLUSIONS: By depressing the Ozurdex implant injector during a 3-second time interval, the impact force of the implant pellet is reduced by about 95%. This new technique will theoretically reduce the risk of retinal injury and vitreous hemorrhage from Ozurdex injections.
UR - http://www.scopus.com/inward/record.url?scp=85061593739&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85061593739&partnerID=8YFLogxK
U2 - 10.3928/23258160-20190129-14
DO - 10.3928/23258160-20190129-14
M3 - Article
C2 - 30768225
AN - SCOPUS:85061593739
SN - 2325-8160
VL - 50
SP - E23-E25
JO - Ophthalmic Surgery Lasers and Imaging Retina
JF - Ophthalmic Surgery Lasers and Imaging Retina
IS - 2
ER -