A new dimension to the biosynthetic products isolated from the sponge Negombata magnifica

Boaz Vilozny, Taro Amagata, Susan L. Mooberry, Phillip Crews

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Latrunculeic acid (3), a novel analogue of latrunculin B (2a), was isolated from the Red Sea sponge Negombata magnifica and characterized. Several known compounds were also isolated, including latrunculin B (2a), 15- methoxylatrunculin B (2b), 16-epi-latrunculin B (4), and latrunculin C (5). In contrast to the other members of the latrunculin family, the novel compound 3 is a polyketide devoid of the normal macrocyclic and thiazolidinone rings present in previously identified members of this family.

Original languageEnglish (US)
Pages (from-to)1055-1057
Number of pages3
JournalJournal of Natural Products
Volume67
Issue number6
DOIs
StatePublished - Jun 2004
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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