TY - JOUR
T1 - A method for the determination of sodium, potassium, magnesium and lithium concentrations in erythrocytes
AU - Frazer, Alan
AU - Secunda, Steven K.
AU - Mendels, Joe
N1 - Funding Information:
* This research was supported by Fart I research funds from the Veterans Administration NIMH grant # I Ro3 MHr6gzo MSM. ** Present address: National Institute of Mental Health. Koclwille, Maryland.
PY - 1972/2
Y1 - 1972/2
N2 - A technique for the rapid and accurate estimation of intra-erythrocyte concentrations of Na, K, Li and Mg is described. CoEDTA is used as a marker to estimate plasma trapped in the red cell column ; the use of this compound constitutes a novel departure from other marker substances previously used. Plasma trapping was found to average close to 3% (v/v) of the packed cell column. RBC electrolyte values obtained from healthy control subjects were shown to be in good agreement with values reported in the literature.
AB - A technique for the rapid and accurate estimation of intra-erythrocyte concentrations of Na, K, Li and Mg is described. CoEDTA is used as a marker to estimate plasma trapped in the red cell column ; the use of this compound constitutes a novel departure from other marker substances previously used. Plasma trapping was found to average close to 3% (v/v) of the packed cell column. RBC electrolyte values obtained from healthy control subjects were shown to be in good agreement with values reported in the literature.
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U2 - 10.1016/0009-8981(72)90026-5
DO - 10.1016/0009-8981(72)90026-5
M3 - Article
C2 - 4621509
AN - SCOPUS:0015295680
SN - 0009-8981
VL - 36
SP - 499
EP - 509
JO - Clinica Chimica Acta
JF - Clinica Chimica Acta
IS - 2
ER -